Democratic presidential hopeful Pete Buttigieg is no Alfred E. Neuman, the freckle-faced, gap-toothed grinning idiot kid who is cover boy of Mad Magazine.

But he might want to pick up the bi-weekly or check out its website to get up-to-speed about the satirical magazine and its mascot.

Donald Trump, 71, referred to the South Bend mayor on Twitter, saying “'Alfred E. Neuman' cannot become president of US.”

Buttigieg, 37, thought he deftly turned the tables on Trump, saying that he had no idea who Trump was talking about, since the iconic Mad icon made his official debut in 1956.

After searching Google, he admitted it was “kind of funny” being compared to Alfred E. but then bored in: “I guess it’s a generational thing. But he’s also the president of the US. I’m surprised he’s not spending more time to salvage this China deal.”

Mad took advantage of the exchange on Twitter, retweeting posts from fans saying they would never vote for a person who doesn’t know who Alfred E. Neuman is.

Neuman’s credo is “What, Me Worry."

Trump may have to worry if Buttigieg succeeds in his long-shot quest to win the Democratic nomination.

Buttigieg is a Harvard grad, Rhodes Scholar, former Navy intelligence officer who served in Afghanistan and speaker of eight languages. He might want to lighten up a bit. Mad would do the trick.

The magazine has a long history of covering Trump, poking fun at his multiple bankruptcies, “Art of the Deal” book and “Apprentice” reality TV show.

Since Trump won the White House, Alfred E. and The Donald have shared multiple covers.

I’ve been a fan of Alfred E. Neuman ever since my dad began buying Mad for me during the late 1960s.

I bet Trump has been a long-time fan of Alfred E., too.